2021 Women's Lacrosse Schedule
| Date | Opponent | Location | Time |
| Wednesday, May 5 | @Mt. St. Mary | Adams Field | 6 p.m. |
| Saturday, May 8 | @Mt. Mercy | Pierce Field at Mulroy Park | 1 p.m. |
| Monday, May 10 | @Nichols | Nichols High School | 4:30 p.m. |
| Wednesday, May 12 | vs. Sacred Heart | Westwood Park Turf | 4:30 p.m. |
| Saturday, May 15 | @Mt. St. Mary | Green Acres | 11 a.m. |
| Monday, May 17 | @Buffalo Seminary | Larkin Field | 4:30 p.m. |
| Friday, May 21 | vs. Nardin | Westwood Park Turf | 4:30 p.m. |
| Saturday, May 22 | @Sacred Heart | Highmark Stadium, Youth Football Field | 11 a.m. |
| Monday, May 24 | vs. Nichols | Westwood Park Turf | 4:30 p.m. |
| Tuesday, June 1 | @High Seed | Playoff Game | TBD |
| Wednesday, June 2 | @High Seed | Playoff Game | TBD |